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Publications as a Principal Investigator

‡ represents undergraduate students

47. KC, S.; Dhungana, R.; Shrestha, B.; Thapa, S.; Khanal, N.; Basnet, P.; Lebrun, R.; Giri, R. "Ni-Catalyzed Regioselective Alkylarylation of Vinylarenes via C(sp3)-C(sp3)/C(sp3)-C(sp2) Bond Formation and Mechanistic Studies" J. Am. Chem. Soc.2018, Just Accepted. Link

Shekhar JACS

46. Gokhale, R.; Thapa, S.; Artyushkova, K.; Giri, R.; Atanassov, P. "Fully Synthetic Approach towards Transition Metal-Nitrogen-Oxygen Reduction Electrocatalysts" ACS Appl. Energ. Mater. 2018, ASAP. Link

Fuel cells

45. Basnet, P.; Dhungana, R. K.; Thapa, S.; Shrestha, B.; KC, S.; Sears, J. M.; Giri, R. "Ni-Catalyzed Regioselective b,d-diarylation of Unactivated Olefins in Ketimines via Ligand-Enabled Contraction of Transient Nickellacycles: Rapid Access to Remotely Diarylated Ketones" J. Am. Chem. Soc.2018, Just Accepted. Link

Highlighted by Synfacts 2018, 14(09), 0964. Link

Prakash beta delta

44. Giri, R.; KC, S. "Strategies toward Dicarbofunctionalization of Unactivated Olefins by Combined Heck Carbometalation and Cross-Coupling" J. Org. Chem. (Synopsis) 2018, accepted. Link (Review Article)

JOC Synopsis

43. Dhungana, R. K.; KC, S.; Basnet, ,P.; Giri, R. "Transition Metal-Catalyzed Dicarbofunctionalization of Unactivated Olefins" Chem. Rec. 2018, accepted. Link (Review Article)


42. KC, S.; Basnet, ,P.; Thapa, S.; Shrestha, B.; Giri, R. "Ni-Catalyzed Regioselective Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling and Application to the Concise Synthesis of Lignan Natural Products" J. Org. Chem. 2018, accepted. Link

Highlighted by Synfacts 2018, 14(5), 0527.  Link


41. Thapa, S.; Dhungana, R. K.; Thapa-Magar, R.; Shrestha, B.; KC, S.; Giri, R. "Ni-Catalyzed Regioselective 1,2-Diarylation of Unactivated Olefins by Stabilising Heck Intermediates as Pyridylsilyl-Coordinated Transient Metallacycles" Chem. Sci. 2018,9, 904-909. Link

Highlighted by Synfacts 2018, 14(4), 0180. Link


40. Shrestha, B.; Basnet, P.; Dhungana, R. K.; KC, S.; Thapa, S.; Sears, J. M.; Giri, R. "Ni-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Olefins by Intercepting Heck Intermediates as Imine-Stabilized Transient Metallacycles" J. Am. Chem. Soc. 2017, 139, 10653–10656. Link

Bijay TOC

39. Thapa, S.; Basnet, P.; Giri, R. "Copper-Catalyzed Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling" J. Am. Chem. Soc. 2017,139, 5700-5703. Link


38. Dhungana, R. K.; Shrestha, B.; Thapa-Magar, R.; Basnet, P.; Giri, R. "Pd-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Unactivated Olefins by a Heck Reaction/Enolate Cyclization Cascade" Org. Lett.2017, 19, 2154-2157.Link


37. Basnet, P.; Thapa, S.; Dickie, D. A.; Giri, R. "Copper-Catalysed Suzuki-Miyaura Coupling of Alkylboron Reagents: Disproportionation of Anionic (Alkyl)(Alkoxy)borates to Anionic Dialkylborates Prior to Transmetalation" Chem. Commun.2016, 52, 11072-11075.Link


36. Shrestha, B.; Thapa, S.; Gurung, S. K.; Pike, R. A. S.; Giri, R. "General Copper-Catalyzed Coupling of Alkyl-, Aryl- and Alkynylaluminum Reagents with Organohalides" J. Org. Chem.2016, 81, 787-802. Link

Highlighted by Synfacts 2016, 14(4), 0403.Link

35. Thapa, S.; Vangala, A. S.; Giri, R. "Copper-Catalyzed Negishi Coupling of Diarylzinc Reagents with Aryl Iodides" Synthesis2016, 48, 504-511. Link (Featured Article)

34. Shrestha, B.; Giri, R. "Copper-Catalyzed Arylation of Alkyl Halides with Arylaluminum Reagents” Beilstein J. Org. Chem.2015, 11, 2400-2407. Link

33. Thapa, S.; Kafle, A.; Gurung, S. K.; Montoya, A.; Riedel, P.; Giri, R. "Ligand-Free Copper-Catalyzed Negishi Coupling of Alkyl-, Aryl- and Alkynylzinc Reagents with Heteroaryl Iodides" Angew. Chem. Int. Ed.2015, 54, 8236-8240.Link

Highlighted by Synfacts 2015; 11(8): 0853. Link

Neghishi Coupling Angew 32. Thapa, S.; Shrestha, B.; Gurung, S. K.; Giri, R. "Copper-Catalysed Cross-Coupling: An Untapped Potential" Org. Biomol. Chem. 2015, 13, 4816-4827. Link

31. Gurung, S.; Thapa, S.; Shrestha, B.; Giri, R. "Copper-Catalysed Cross-Couplings of Arylboronate Esters with Aryl and Heteroaryl Iodides and Bromides" Org. Chem. Front. 2015, 2, 649-653. Link

Highlighted by Organic Process Research & Development.

Org. Process Res. Dev.2015, 19, 950−956. Link

30. Thapa, S.; Basnet, P.; Gurung, S. K.; Giri, R. "Copper-Catalysed Cross-Coupling of Arylzirconium Reagents with Aryl and Heteroaryl Iodides" Chem. Commun.2015, 51, 4009-4012. Link

Highlighted by Synfacts 2015, 11(5), 0533.  Link

Zr Scheme

29. Giri, R.; Thapa, S. "Copper-Catalyzed Cross-Couplings of Organometallic Reagents with and without Assistance from PN Ligands" Synlett2015, 26, 709-715. (Synpacts) Link

Featured on theCover Page. Link

28. Thapa, S.; Gurung, S. K.; Giri, R. "2-(Diphenylphosphino)aniline" Electronic Encyclopedia of the Reagents for Organic Synthesis (eEROS), 2015.Link

27. Thapa, S.; Gurung, S. K.; Dickie, D. A.; Giri, R. "Copper-Catalyzed Coupling of Triaryl- and Trialkylindium Reagents with Aryl Iodides and Bromides via Consecutive Transmetalations" Angew. Chem. Int. Ed.2014, 53, 11620-11624. Link

Highlighted by Synfacts 2015; 11(1): 0084.Link

Synfacts 2015; 11(1): 0084.

26. Gurung, S. K.; Thapa, S.; Shrestha, B.; Giri, R. "Copper-Catalyzed Cross-Couplings of Aryl- and Heteroaryltri-ethoxysilanes with Aryl and Heteroaryl Iodides and Bromides" Synthesis2014, 46, 1933-1937. Link

25. Giri, R.; Thapa, S.; Kafle, A. "Pd-Catalysed, Directed C-H Coupling with Organometallics" Adv. Syn. Catal.2014, 356, 1395-1411. Link

24. Gurung, S. K.; Thapa, S.; Kafle, A.; Dickie, D. A.; Giri, R. "Copper-Catalyzed Suzuki-Miyaura Coupling of Arylboronate Esters: Transmetalation with (PN)CuF and Identification of Intermediates" Org. Lett.2014, 16, 1264–1267. Link

Copper-Catalyzed Suzuki-Miyaura Coupling of Arylboronate Esters

23. Gurung, S. K.; Thapa, S.; Vangala, A. S.; Giri, R. "Copper-Catalyzed Hiyama Coupling of (Hetero)aryltriethoxy-silanes with (Hetero)aryl Iodides" Org. Lett.2013, 15, 5378-5381. LinkCopper-Catalyzed Hiyama Coupling of (Hetero)aryltriethoxy-silanes with (Hetero)aryl Iodides

Publications as a Graduate Student and Postdoc

22. Giri, R.; Brusoe, A.; Troshin, K.; Wang, J, Y.; Font, M.; Hartwig, J. F. "Mechanism of the Ullmann Biaryl Ether Synthesis Catalyzed by Complexes of Anionic Ligands: Evidence for the Reaction of Iodoarenes with Ligated Anionic CuI Intermediates" J. Am. Chem. Soc.2018, 140, 793–806. Link

21. Gong, W.; Zhang, G.; Liu, T.; Giri, R.; Yu, J.-Q. "Site-selective C(sp3)–H Functionalization of Di-, Tri- and Tetrapeptides at the N-Terminus" J. Am. Chem. Soc.2014, 136, 16940–16946. Link

20. Giri, R.; Lan, Yu.; Liu, P.; Houk, K. N.; Yu, J.-Q. "Understanding Reactivity and Stereoselectivity in Palladium-Catalyzed Diastereoselective sp3 C-H Bond Activation: Intermediate Characterization and Computational Studies" J. Am. Chem. Soc.2012, 134, 14118. Link

19. Giri, R.; Hartwig, J. F. "Cu(I) Amido Complexes in the Ullmann Reaction. Reactions of Cu(I)-Amido Complexes with Iodoarenes with and without Autocatalysis by CuI" J. Am. Chem. Soc.2010, 132, 15860. Link

18. Tye, J. W.; Weng, Z.; Giri, R.; Hartwig, J. F. "Copper(I) Phenoxide Complexes in the Etherification of Aryl Halides" Angew. Chem., Int. Ed.2010, 49, 2185. Link

17. Giri, R.; Lam, J. K.; Yu, J.-Q. "Synthetic Applications of Pd(II)-Catalyzed C-H Carboxylation and Mechanistic Insights: Expedient Routes to Anthranilic Acids, Oxazolinones, and Quinazolinones" J. Am. Chem. Soc.2010, 132, 686. Link

16. Giri, R.; Shi, B.-F.; Engle, K. M.; Maugel, N.; Yu, J.-Q. "Transition Metal-Catalyzed C-H Activation Reactions: Diastereoselectivity and Enantioselectivity" Chem. Soc. Rev.2009, 38, 3242. Link

15. Chen, X.; Dobereiner, G.; Hao, X.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. "Cu(II)-Mediated Oxidative Dimerization of 2-Phenylpyridine Derivatives" Tetrahedron2009, 65, 3085. Link

14. Giri, R.; Yu, J.-Q. "Synthesis of 1,2-and 1,3-Dicarboxylic Acids via Pd(II)-Catalyzed Carboxylation of Aryl and Vinyl C-H Bonds" J. Am. Chem. Soc.2008, 130, 14082. Link

13. Giri, R.; Maugel, N.; Foxman, B. M.; Yu, J.-Q. "Dehydrogenation of Alkyl Groups via Remote C-H Activation: Converting a Propyl Group into a -Allylic Complex" Organometallics2008, 27, 1667. Link

12. Giri, R.; Yu, J.-Q. "Iodine Monoacetate" Electronic Encyclopaedia of the Reagents for Organic Synthesis (eEROS)2008. Link

11. Li, J.-J.; Giri, R.; Yu, J.-Q. "Remote C-H Bond Functionalization Reveals the Distance-dependant Isotope Effect" Tetrahedron2008, 64, 6979. Link

10. Mei, T.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. "Pd(II)-Catalyzed mono-Selective ortho-Halogenation of Arene Carboxylic Acids Assisted by Counter Cations: An Orthogonal Method to Directed ortho-Lithiation" Angew. Chem., Int. Ed.2008, 47, 5215. Link

9. Wang, D.-H; Wasa, M.; Giri, R.; Yu, J.-Q. "Pd(II)-catalyzed Cross-Coupling of sp2 and sp3 Boronic Acids Using Air as the Oxidant" J. Am. Chem. Soc.2008, 130, 7190. Link (Highlighted in Synform 2008/09. Link)

8. Giri, R.; Maugel, N.; Li, J.-J.; Wang, D.-H; Breazzano, S. P.; Saunders, L. B.; Yu, J.-Q. "Palladium-Catalyzed Methylation and Arylation of sp2 and sp3 C-H Bonds in Simple Carboxylic Acids" J. Am. Chem. Soc.2007, 129, 3510. Link

7. Giri, R.; Wasa, M.; Breazzano, S. P.; Yu, J.-Q. "Converting gem-Dimethyl Groups into Cyclopropanes via Pd-Catalyzed Sequential C-H Activation and Radical Cyclization" Org. Lett.2006, 8, 5685. Link

6. Yu, J.-Q.; Giri, R.; Chen, X. "σ-Chelation-directed C-H Functionalizations using Pd(II) and Cu(II) Catalysts: Regioselectivity, Stereoselectivity and Catalytic Turnover" Org. Biomol. Chem.2006, 4, 4041. Link

5. Giri, R.; Chen, X.; Yu, J.-Q. "Palladium-Catalyzed Asymmetric Iodination of Unactivated C-H Bonds under Mild Conditions" Angew. Chem., Int. Ed.2005, 44, 2112. Link (Highlighted in Synfacts 2005, 0, 0052-0052. Link)

4. Giri, R.; Liang, J.; Lei, J.-G.; Li, J.-J.; Wang, D.-H.; Chen, X.; Naggar, I. C.; Guo, C.; Foxman, B. M.; Yu, J. Q. "Palladium-Catalyzed Stereoselective Oxidation of Methyl Groups by Inexpensive Oxidants under Mild Conditions: a Dual Role for Carboxylic Anhydrides in Catalytic C-H Bond Oxidation" Angew. Chem., Int. Ed.2005, 44, 7420. Link

3. Giri, R.; Chen, X.; Hao, X.-H.; Li, J.-J.; Liang, J.; Fan, Z.-P.; Yu, J.-Q. "Catalytic and Stereoselective Iodination of Prochiral C-H Bonds" Tetrahedron: Asymmetry2005, 16, 3502. Link

2. Li, Y.; Llewellyn, N. M.; Giri, R.; Huang, F.; Spencer, J. B. "Biosynthesis of the Unique Amino Acid Side Chain of Butirosin: Possible Protective-Group Chemistry in an Acyl Carrier Protein-Mediated Pathway" Chem. Biol.2005, 12, 665. Link

1. Bajracharya, G. B.; Pokhrel, D.; Giri, R.; Tuladhar, S. M. "Potentially Anti-carcinogenic Flavonoids in Vegetables, Fruits and Spices" Npl. J. Sci. Tech.2000, 2, 17. Link